Improving Targets for the Prevention of Drug Use Disorders: Sociodemographic Predictors of Transitions Across Drug Use Stages in the National Comorbidity Survey Replication
Identifieur interne : 008588 ( Main/Exploration ); précédent : 008587; suivant : 008589Improving Targets for the Prevention of Drug Use Disorders: Sociodemographic Predictors of Transitions Across Drug Use Stages in the National Comorbidity Survey Replication
Auteurs : Joel Swendsen [France] ; James C. Anthony [États-Unis] ; Kevin P. Conway [États-Unis] ; Louisa Degenhardt [Australie] ; Lisa Dierker [États-Unis] ; Meyer Glantz [États-Unis] ; Jianping He [États-Unis] ; Amanda Kalaydjian [États-Unis] ; Ronald C. Kessler [États-Unis] ; Nancy Sampson [États-Unis] ; Kathleen R. Merikangas [États-Unis]Source :
- Preventive medicine [ 0091-7435 ] ; 2008.
Abstract
Models of drug use etiology and prevention require precise information concerning the expression of population-based risk factors across the continuum of drug use. However, the majority of previous epidemiologic research on this topic has not addressed transitions between specific drug stages. The present investigation examined the sociodemographic predictors of progression across six stages of drug use in the National Comorbidity Survey Replication (NCS-R), a nationally representative household survey of the U.S. population conducted between February, 2001 and April, 2003.
Lifetime history of opportunity to use illicit substances, initial drug use, and DSM-IV drug use disorders were collected using in-person structured diagnostic interviews.
The median age of first opportunity to use drugs as well as drug use, abuse and dependence each occurred prior to age 20, while the median remission from abuse and dependence occurred at 26 and 30 years, respectively. Most sociodemographic variables, in particular sex and ethnicity, demonstrated highly differential associations with transitions depending on the stage examined.
The findings may partially explain the effectiveness of strategies designed to reduce drug use, abuse and dependence, and indicate that increased correspondence is needed between available epidemiologic data and existing models of etiology or prevention.
Url:
DOI: 10.1016/j.ypmed.2008.09.009
PubMed: 18926848
PubMed Central: 2933380
Affiliations:
- Australie, France, États-Unis
- Aquitaine, Connecticut, Maryland, Massachusetts, Michigan, Nouvelle-Aquitaine, Nouvelle-Galles du Sud
- Bordeaux, Cambridge (Massachusetts), East Lansing, Sydney
- Université Harvard, Université d'État du Michigan
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Anthony</name><affiliation wicri:level="4"><nlm:aff id="A2"> Department of Epidemiology, Michigan State University, Lansing, Michigan, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Epidemiology, Michigan State University, Lansing, Michigan</wicri:regionArea><placeName><region type="state">Michigan</region><settlement type="city">East Lansing</settlement></placeName><orgName type="university">Université d'État du Michigan</orgName></affiliation></author><author><name sortKey="Conway, Kevin P" sort="Conway, Kevin P" uniqKey="Conway K" first="Kevin P." last="Conway">Kevin P. Conway</name><affiliation wicri:level="1"><nlm:aff id="A3"> Division of Epidemiology, Services, and Prevention Research, National Institute on Drug Abuse, National Institutes of Health, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Epidemiology, Services, and Prevention Research, National Institute on Drug Abuse, National Institutes of Health</wicri:regionArea><wicri:noRegion>National Institutes of Health</wicri:noRegion></affiliation></author><author><name sortKey="Degenhardt, Louisa" sort="Degenhardt, Louisa" uniqKey="Degenhardt L" first="Louisa" last="Degenhardt">Louisa Degenhardt</name><affiliation wicri:level="3"><nlm:aff id="A4"> National Drug and Alcohol Research Centre, University of NSW, Sydney, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea> National Drug and Alcohol Research Centre, University of NSW, Sydney</wicri:regionArea><placeName><settlement type="city">Sydney</settlement><region type="état">Nouvelle-Galles du Sud</region></placeName></affiliation></author><author><name sortKey="Dierker, Lisa" sort="Dierker, Lisa" uniqKey="Dierker L" first="Lisa" last="Dierker">Lisa Dierker</name><affiliation wicri:level="2"><nlm:aff id="A5"> Wesleyan University, Department of Psychology, Middletown, Connecticut, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Wesleyan University, Department of Psychology, Middletown, Connecticut</wicri:regionArea><placeName><region type="state">Connecticut</region></placeName></affiliation></author><author><name sortKey="Glantz, Meyer" sort="Glantz, Meyer" uniqKey="Glantz M" first="Meyer" last="Glantz">Meyer Glantz</name><affiliation wicri:level="1"><nlm:aff id="A3"> Division of Epidemiology, Services, and Prevention Research, National Institute on Drug Abuse, National Institutes of Health, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Epidemiology, Services, and Prevention Research, National Institute on Drug Abuse, National Institutes of Health</wicri:regionArea><wicri:noRegion>National Institutes of Health</wicri:noRegion></affiliation></author><author><name sortKey="He, Jianping" sort="He, Jianping" uniqKey="He J" first="Jianping" last="He">Jianping He</name><affiliation wicri:level="2"><nlm:aff id="A6"> Intramural Research Program of the National Institutes of Health, National Institute of Mental Health, Bethesda, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Intramural Research Program of the National Institutes of Health, National Institute of Mental Health, Bethesda, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Kalaydjian, Amanda" sort="Kalaydjian, Amanda" uniqKey="Kalaydjian A" first="Amanda" last="Kalaydjian">Amanda Kalaydjian</name><affiliation wicri:level="2"><nlm:aff id="A6"> Intramural Research Program of the National Institutes of Health, National Institute of Mental Health, Bethesda, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Intramural Research Program of the National Institutes of Health, National Institute of Mental Health, Bethesda, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Kessler, Ronald C" sort="Kessler, Ronald C" uniqKey="Kessler R" first="Ronald C." last="Kessler">Ronald C. Kessler</name><affiliation wicri:level="4"><nlm:aff id="A7"> Department of Health Policy, Harvard University, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Health Policy, Harvard University, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region><settlement type="city">Cambridge (Massachusetts)</settlement></placeName><orgName type="university">Université Harvard</orgName></affiliation></author><author><name sortKey="Sampson, Nancy" sort="Sampson, Nancy" uniqKey="Sampson N" first="Nancy" last="Sampson">Nancy Sampson</name><affiliation wicri:level="4"><nlm:aff id="A7"> Department of Health Policy, Harvard University, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Health Policy, Harvard University, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region><settlement type="city">Cambridge (Massachusetts)</settlement></placeName><orgName type="university">Université Harvard</orgName></affiliation></author><author><name sortKey="Merikangas, Kathleen R" sort="Merikangas, Kathleen R" uniqKey="Merikangas K" first="Kathleen R." last="Merikangas">Kathleen R. Merikangas</name><affiliation wicri:level="2"><nlm:aff id="A6"> Intramural Research Program of the National Institutes of Health, National Institute of Mental Health, Bethesda, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Intramural Research Program of the National Institutes of Health, National Institute of Mental Health, Bethesda, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author></analytic><series><title level="j">Preventive medicine</title><idno type="ISSN">0091-7435</idno><idno type="eISSN">1096-0260</idno><imprint><date when="2008">2008</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec id="S1"><title>Objectives</title><p id="P2">Models of drug use etiology and prevention require precise information concerning the expression of population-based risk factors across the continuum of drug use. However, the majority of previous epidemiologic research on this topic has not addressed transitions between specific drug stages. The present investigation examined the sociodemographic predictors of progression across six stages of drug use in the National Comorbidity Survey Replication (NCS-R), a nationally representative household survey of the U.S. population conducted between February, 2001 and April, 2003.</p></sec><sec sec-type="methods" id="S2"><title>Methods</title><p id="P3">Lifetime history of opportunity to use illicit substances, initial drug use, and DSM-IV drug use disorders were collected using in-person structured diagnostic interviews.</p></sec><sec id="S3"><title>Results</title><p id="P4">The median age of first opportunity to use drugs as well as drug use, abuse and dependence each occurred prior to age 20, while the median remission from abuse and dependence occurred at 26 and 30 years, respectively. Most sociodemographic variables, in particular sex and ethnicity, demonstrated highly differential associations with transitions depending on the stage examined.</p></sec><sec id="S4"><title>Conclusions</title><p id="P5">The findings may partially explain the effectiveness of strategies designed to reduce drug use, abuse and dependence, and indicate that increased correspondence is needed between available epidemiologic data and existing models of etiology or prevention.</p></sec></div></front></TEI><affiliations><list><country><li>Australie</li><li>France</li><li>États-Unis</li></country><region><li>Aquitaine</li><li>Connecticut</li><li>Maryland</li><li>Massachusetts</li><li>Michigan</li><li>Nouvelle-Aquitaine</li><li>Nouvelle-Galles du Sud</li></region><settlement><li>Bordeaux</li><li>Cambridge (Massachusetts)</li><li>East Lansing</li><li>Sydney</li></settlement><orgName><li>Université Harvard</li><li>Université d'État du Michigan</li></orgName></list><tree><country name="France"><region name="Nouvelle-Aquitaine"><name sortKey="Swendsen, Joel" sort="Swendsen, Joel" uniqKey="Swendsen J" first="Joel" last="Swendsen">Joel Swendsen</name></region></country><country name="États-Unis"><region name="Michigan"><name sortKey="Anthony, James C" sort="Anthony, James C" uniqKey="Anthony J" first="James C." last="Anthony">James C. Anthony</name></region><name sortKey="Conway, Kevin P" sort="Conway, Kevin P" uniqKey="Conway K" first="Kevin P." last="Conway">Kevin P. Conway</name><name sortKey="Dierker, Lisa" sort="Dierker, Lisa" uniqKey="Dierker L" first="Lisa" last="Dierker">Lisa Dierker</name><name sortKey="Glantz, Meyer" sort="Glantz, Meyer" uniqKey="Glantz M" first="Meyer" last="Glantz">Meyer Glantz</name><name sortKey="He, Jianping" sort="He, Jianping" uniqKey="He J" first="Jianping" last="He">Jianping He</name><name sortKey="Kalaydjian, Amanda" sort="Kalaydjian, Amanda" uniqKey="Kalaydjian A" first="Amanda" last="Kalaydjian">Amanda Kalaydjian</name><name sortKey="Kessler, Ronald C" sort="Kessler, Ronald C" uniqKey="Kessler R" first="Ronald C." last="Kessler">Ronald C. Kessler</name><name sortKey="Merikangas, Kathleen R" sort="Merikangas, Kathleen R" uniqKey="Merikangas K" first="Kathleen R." last="Merikangas">Kathleen R. Merikangas</name><name sortKey="Sampson, Nancy" sort="Sampson, Nancy" uniqKey="Sampson N" first="Nancy" last="Sampson">Nancy Sampson</name></country><country name="Australie"><region name="Nouvelle-Galles du Sud"><name sortKey="Degenhardt, Louisa" sort="Degenhardt, Louisa" uniqKey="Degenhardt L" first="Louisa" last="Degenhardt">Louisa Degenhardt</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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